K60N (p.Lys60Asn) variant of CHM (P24386)
K60N (p.Lys60Asn) in CHM (P24386) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
K60N (p.Lys60Asn) variant details
- p.Lys60Asn
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.167
- REVEL 0.04
- MetaLR 0.14
- MetaSVM -0.95
- CADD 21.10
- PolyPhen-2 0.02
- SIFT 0.11
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available