F9L (p.Phe9Leu) variant of CHM (P24386)
F9L (p.Phe9Leu) in CHM (P24386) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
F9L (p.Phe9Leu) variant details
- p.Phe9Leu
- gnomAD rs1278864845
- Missense
- Variant Prioritization Score for Impact Estimate 0.725
- REVEL 0.83
- MetaLR 0.75
- MetaSVM 0.66
- CADD 24.70
- PolyPhen-2 0.59
- SIFT 0.06
- Most common in the Latino/Admixed American population (allele frequency 2.9e-05)
- Structural context available