L25M (p.Leu25Met) variant of CHEK1 (O14757)
L25M (p.Leu25Met) in CHEK1 (O14757) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
L25M (p.Leu25Met) variant details
- p.Leu25Met
- gnomAD 11-125625821-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.216
- CADD 9.57
- Population evidence available
- Structural context available
- Literature evidence available