L11P (p.Leu11Pro) variant of CHEK1 (O14757)
L11P (p.Leu11Pro) in CHEK1 (O14757) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
L11P (p.Leu11Pro) variant details
- p.Leu11Pro
- gnomAD 11-125625786-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.192
- CADD 15.70
- Most common in the Non-Finnish European population (allele frequency 6.4e-06)
- Structural context available
- Literature evidence available