W19L (p.Trp19Leu) variant of CFTR (P13569)
W19L (p.Trp19Leu) in CFTR (P13569) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.95 / 1. The record also includes structural context.
W19L (p.Trp19Leu) variant details
- p.Trp19Leu
- NCI-TCGA TCGA novel
- Variant assessed as somatic; high impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.948
- REVEL 0.94
- ESM-1b 1.00
- AlphaMissense 0.91
- MetaLR 0.94
- MetaSVM 1.09
- SIFT 0.00
- UniProt: Variant assessed as somatic; high impact.
- Structural context available