T91S (p.Thr91Ser) variant of CFH (Complement factor H)
T91S (p.Thr91Ser) in CFH (Complement factor H) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
T91S (p.Thr91Ser) variant details
- p.Thr91Ser
- rs771527214
- gnomAD 1-196673884-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.27
- REVEL 0.23
- MetaLR 0.25
- MetaSVM -0.87
- CADD 22.80
- PolyPhen-2 0.81
- SIFT 0.19
- Population evidence available
- Structural context available
- Literature evidence available