C85Y (p.Cys85Tyr) variant of CFH (Complement factor H)
C85Y (p.Cys85Tyr) in CFH (Complement factor H) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.89 / 1. The record also includes population frequency data, published literature, and structural context.
C85Y (p.Cys85Tyr) variant details
- p.Cys85Tyr
- gnomAD 1-196673866-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.895
- REVEL 0.97
- CADD 27.00
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available