Y74C (p.Tyr74Cys) variant of CETP (P11597)
Y74C (p.Tyr74Cys) in CETP (P11597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, published literature, and structural context.
Y74C (p.Tyr74Cys) variant details
- p.Tyr74Cys
- gnomAD 16-56963112-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.553
- REVEL 0.37
- CADD 22.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available