L2V (p.Leu2Val) variant of CETP (P11597)
L2V (p.Leu2Val) in CETP (P11597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
L2V (p.Leu2Val) variant details
- p.Leu2Val
- gnomAD rs2056025839
- Missense
- Variant Prioritization Score for Impact Estimate 0.13
- REVEL 0.06
- CADD 14.30
- PolyPhen-2 0.15
- SIFT 0.04
- Most common in the HGDP:DRUZE population (allele frequency 0.014)
- Structural context available