L12R (p.Leu12Arg) variant of CETP (P11597)
L12R (p.Leu12Arg) in CETP (P11597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
L12R (p.Leu12Arg) variant details
- p.Leu12Arg
- gnomAD rs1403262620
- Missense
- Variant Prioritization Score for Impact Estimate 0.291
- REVEL 0.27
- CADD 23.10
- PolyPhen-2 0.92
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available