K46R (p.Lys46Arg) variant of CETP (P11597)
K46R (p.Lys46Arg) in CETP (P11597) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
K46R (p.Lys46Arg) variant details
- p.Lys46Arg
- TOPMed rs1230953022
- gnomAD rs1230953022
- Missense
- Variant Prioritization Score for Impact Estimate 0.273
- REVEL 0.05
- CADD 19.40
- PolyPhen-2 0.20
- SIFT 0.08
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available