E43* (p.Glu43Ter) variant of CETP (P11597)
E43* (p.Glu43Ter) in CETP (P11597) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
E43* (p.Glu43Ter) variant details
- p.Glu43Ter
- NCI-TCGA TCGA novel
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.416
- CADD 35.00
- UniProt: Variant assessed as somatic; high impact.
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available