A15D (p.Ala15Asp) variant of CETP (P11597)
A15D (p.Ala15Asp) in CETP (P11597) is a missense change. Clinical records from EBI and UniProt describe it as benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
A15D (p.Ala15Asp) variant details
- p.Ala15Asp
- 1000Genomes rs34065661
- ESP rs34065661
- ExAC rs34065661
- TOPMed rs34065661
- Benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.173
- REVEL 0.06
- AlphaMissense 0.08
- MetaLR 0.00
- MetaSVM -1.01
- CADD 12.90
- PolyPhen-2 0.08
- EBI: Benign (in dbSNP:rs34065661)
- UniProt: Benign (in dbSNP:rs34065661)
- Most common in the Non-Finnish European population (allele frequency 4.4e-05)
- Structural context available