Y45C (p.Tyr45Cys) variant of CEBPE (Q15744)
Y45C (p.Tyr45Cys) in CEBPE (Q15744) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes structural context.
Y45C (p.Tyr45Cys) variant details
- p.Tyr45Cys
- NCI-TCGA Cosmic COSV9924
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.598
- REVEL 0.60
- ESM-1b 1.00
- AlphaMissense 0.90
- MetaLR 0.31
- MetaSVM -0.41
- SIFT 0.02
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available