Y80C (p.Tyr80Cys) variant of CDX2 (Homeobox protein CDX-2)
Y80C (p.Tyr80Cys) in CDX2 (Homeobox protein CDX-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data.
Y80C (p.Tyr80Cys) variant details
- p.Tyr80Cys
- 1000Genomes rs546556192
- Missense
- Variant Prioritization Score for Impact Estimate 0.429
- REVEL 0.46
- MetaLR 0.38
- MetaSVM -0.40
- CADD 23.10
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 0.0019)