Y43C (p.Tyr43Cys) variant of CDX2 (Homeobox protein CDX-2)
Y43C (p.Tyr43Cys) in CDX2 (Homeobox protein CDX-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data.
Y43C (p.Tyr43Cys) variant details
- p.Tyr43Cys
- ExAC rs771731984
- gnomAD rs771731984
- Missense
- Variant Prioritization Score for Impact Estimate 0.606
- REVEL 0.70
- MetaLR 0.45
- MetaSVM -0.06
- CADD 29.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the 1KG:CEU population (allele frequency 0.0042)