Y37H (p.Tyr37His) variant of CDX2 (Homeobox protein CDX-2)
Y37H (p.Tyr37His) in CDX2 (Homeobox protein CDX-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data.
Y37H (p.Tyr37His) variant details
- p.Tyr37His
- ExAC rs772797601
- TOPMed rs772797601
- gnomAD rs772797601
- Missense
- Variant Prioritization Score for Impact Estimate 0.496
- REVEL 0.47
- MetaLR 0.40
- MetaSVM -0.20
- CADD 32.00
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the HGDP:DAI population (allele frequency 0.22)