S109R (p.Ser109Arg) variant of CDX2 (Homeobox protein CDX-2)
S109R (p.Ser109Arg) in CDX2 (Homeobox protein CDX-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data.
S109R (p.Ser109Arg) variant details
- p.Ser109Arg
- ExAC rs376274339
- TOPMed rs376274339
- gnomAD rs376274339
- Missense
- Variant Prioritization Score for Impact Estimate 0.261
- REVEL 0.14
- MetaLR 0.14
- MetaSVM -0.97
- CADD 20.50
- PolyPhen-2 0.78
- SIFT 0.01
- Most common in the 1KG:CEU population (allele frequency 0.0042)