H117Y (p.His117Tyr) variant of CDX2 (Homeobox protein CDX-2)
H117Y (p.His117Tyr) in CDX2 (Homeobox protein CDX-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
H117Y (p.His117Tyr) variant details
- p.His117Tyr
- gnomAD rs1359855388
- Missense
- Variant Prioritization Score for Impact Estimate 0.292
- REVEL 0.09
- MetaLR 0.13
- MetaSVM -0.82
- CADD 22.80
- PolyPhen-2 0.46
- SIFT 0.01
- Most common in the HGDP:XIBO population (allele frequency 0.056)
- Structural context available