H117D (p.His117Asp) variant of CDX2 (Homeobox protein CDX-2)
H117D (p.His117Asp) in CDX2 (Homeobox protein CDX-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
H117D (p.His117Asp) variant details
- p.His117Asp
- gnomAD rs1359855388
- Missense
- Variant Prioritization Score for Impact Estimate 0.305
- REVEL 0.15
- MetaLR 0.09
- MetaSVM -1.02
- CADD 18.50
- PolyPhen-2 0.01
- SIFT 0.05
- Most common in the 1KG:CEU population (allele frequency 0.0042)
- Structural context available