H114R (p.His114Arg) variant of CDX2 (Homeobox protein CDX-2)
H114R (p.His114Arg) in CDX2 (Homeobox protein CDX-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
H114R (p.His114Arg) variant details
- p.His114Arg
- TOPMed rs1869469940
- Missense
- Variant Prioritization Score for Impact Estimate 0.252
- REVEL 0.14
- MetaLR 0.08
- MetaSVM -1.04
- CADD 15.70
- PolyPhen-2 0.06
- SIFT 0.10
- Most common in the REMAINING population (allele frequency 0.00045)
- Structural context available