D8G (p.Asp8Gly) variant of CDX2 (Homeobox protein CDX-2)
D8G (p.Asp8Gly) in CDX2 (Homeobox protein CDX-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data.
D8G (p.Asp8Gly) variant details
- p.Asp8Gly
- ExAC rs759160901
- TOPMed rs759160901
- gnomAD rs759160901
- Missense
- Variant Prioritization Score for Impact Estimate 0.712
- REVEL 0.78
- MetaLR 0.77
- MetaSVM 0.67
- CADD 31.00
- PolyPhen-2 0.86
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 0.00012)