A51T (p.Ala51Thr) variant of CDX2 (Homeobox protein CDX-2)
A51T (p.Ala51Thr) in CDX2 (Homeobox protein CDX-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
A51T (p.Ala51Thr) variant details
- p.Ala51Thr
- ExAC rs768601101
- TOPMed rs768601101
- gnomAD rs768601101
- Missense
- Variant Prioritization Score for Impact Estimate 0.419
- REVEL 0.22
- MetaLR 0.43
- MetaSVM -0.53
- CADD 22.10
- PolyPhen-2 0.54
- SIFT 0.67
- Most common in the Latino/Admixed American population (allele frequency 5.6e-05)
- Structural context available