A111T (p.Ala111Thr) variant of CDX2 (Homeobox protein CDX-2)
A111T (p.Ala111Thr) in CDX2 (Homeobox protein CDX-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
A111T (p.Ala111Thr) variant details
- p.Ala111Thr
- TOPMed rs1279218920
- gnomAD rs1279218920
- Missense
- Variant Prioritization Score for Impact Estimate 0.143
- REVEL 0.04
- MetaLR 0.06
- MetaSVM -1.05
- CADD 14.00
- PolyPhen-2 0.21
- SIFT 0.10
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available