A111S (p.Ala111Ser) variant of CDX2 (Homeobox protein CDX-2)
A111S (p.Ala111Ser) in CDX2 (Homeobox protein CDX-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
A111S (p.Ala111Ser) variant details
- p.Ala111Ser
- TOPMed rs1279218920
- gnomAD rs1279218920
- Missense
- Variant Prioritization Score for Impact Estimate 0.137
- REVEL 0.06
- MetaLR 0.05
- MetaSVM -1.01
- CADD 10.10
- PolyPhen-2 0.04
- SIFT 0.13
- Most common in the REMAINING population (allele frequency 0.0019)
- Structural context available