V36L (p.Val36Leu) variant of CDKN1B (P46527)
V36L (p.Val36Leu) in CDKN1B (P46527) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
V36L (p.Val36Leu) variant details
- p.Val36Leu
- ExAC rs753931778
- gnomAD rs753931778
- Missense
- Variant Prioritization Score for Impact Estimate 0.684
- REVEL 0.63
- CADD 25.00
- PolyPhen-2 0.44
- SIFT 0.01
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available