S10S (p.Ser10Ser) variant of CDKN1B (P46527)
S10S (p.Ser10Ser) in CDKN1B (P46527) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
S10S (p.Ser10Ser) variant details
- p.Ser10Ser
- rs990433180
- gnomAD 12-12717869-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.416
- AlphaMissense 0.99
- MetaLR 0.69
- MetaSVM 0.32
- CADD 13.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)
- Structural context available
- Literature evidence available