R43L (p.Arg43Leu) variant of CDKN1B (P46527)
R43L (p.Arg43Leu) in CDKN1B (P46527) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
R43L (p.Arg43Leu) variant details
- p.Arg43Leu
- cosmic curated COSV10955
- gnomAD rs1174071842
- Missense
- Variant Prioritization Score for Impact Estimate 0.702
- REVEL 0.61
- CADD 32.00
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available