R19W (p.Arg19Trp) variant of CDKN1B (P46527)
R19W (p.Arg19Trp) in CDKN1B (P46527) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data, published literature, and structural context.
R19W (p.Arg19Trp) variant details
- p.Arg19Trp
- gnomAD 12-12717894-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.52
- REVEL 0.61
- CADD 23.30
- PolyPhen-2 0.04
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available