V25D (p.Val25Asp) variant of CDKN1A (P38936)
V25D (p.Val25Asp) in CDKN1A (P38936) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and published literature.
V25D (p.Val25Asp) variant details
- p.Val25Asp
- gnomAD 22-46248172-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.354
- REVEL 0.28
- MetaLR 0.28
- MetaSVM -0.55
- CADD 24.90
- PolyPhen-2 0.93
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Literature evidence available