L37S (p.Leu37Ser) variant of CDKN1A (P38936)
L37S (p.Leu37Ser) in CDKN1A (P38936) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
L37S (p.Leu37Ser) variant details
- p.Leu37Ser
- rs759612189
- gnomAD 22-46247217-G-GGA
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.466
- CADD 27.90
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available