G14S (p.Gly14Ser) variant of CDKN1A (P38936)
G14S (p.Gly14Ser) in CDKN1A (P38936) is a missense change. Clinical records from ClinVar and UniProt describe it as likely benign in the context of not specified. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data.
G14S (p.Gly14Ser) variant details
- p.Gly14Ser
- rs576307617
- cosmic curated COSV10584
- 1000Genomes rs576307617
- ExAC rs576307617
- Likely benign
- not specified
- Missense
- Variant Prioritization Score for Impact Estimate 0.403
- AlphaMissense 0.13
- MetaLR 0.24
- MetaSVM -0.48
- PolyPhen-2 0.98
- SIFT 0.10
- MutPred 0.14
- ClinVar: Likely benign (not specified)
- UniProt: Likely benign
- Population evidence available