R39P (p.Arg39Pro) variant of CDK9 (Cyclin-dependent kinase 9)
R39P (p.Arg39Pro) in CDK9 (Cyclin-dependent kinase 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
R39P (p.Arg39Pro) variant details
- p.Arg39Pro
- TOPMed rs914635422
- gnomAD rs914635422
- Missense
- Variant Prioritization Score for Impact Estimate 0.578
- REVEL 0.41
- CADD 28.60
- PolyPhen-2 0.81
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available