R39C (p.Arg39Cys) variant of CDK9 (Cyclin-dependent kinase 9)
R39C (p.Arg39Cys) in CDK9 (Cyclin-dependent kinase 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
R39C (p.Arg39Cys) variant details
- p.Arg39Cys
- gnomAD rs1283944680
- Missense
- Variant Prioritization Score for Impact Estimate 0.571
- REVEL 0.40
- CADD 28.60
- PolyPhen-2 0.88
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available