R37G (p.Arg37Gly) variant of CDK9 (Cyclin-dependent kinase 9)
R37G (p.Arg37Gly) in CDK9 (Cyclin-dependent kinase 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
R37G (p.Arg37Gly) variant details
- p.Arg37Gly
- TOPMed rs988782815
- Missense
- Variant Prioritization Score for Impact Estimate 0.383
- REVEL 0.29
- CADD 29.30
- PolyPhen-2 0.53
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 9e-05)
- Structural context available