L22F (p.Leu22Phe) variant of CDK9 (Cyclin-dependent kinase 9)
L22F (p.Leu22Phe) in CDK9 (Cyclin-dependent kinase 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
L22F (p.Leu22Phe) variant details
- p.Leu22Phe
- ExAC rs770049111
- TOPMed rs770049111
- gnomAD rs770049111
- Missense
- Variant Prioritization Score for Impact Estimate 0.372
- REVEL 0.16
- CADD 25.50
- PolyPhen-2 0.56
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available