E32K (p.Glu32Lys) variant of CDK9 (Cyclin-dependent kinase 9)
E32K (p.Glu32Lys) in CDK9 (Cyclin-dependent kinase 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
E32K (p.Glu32Lys) variant details
- p.Glu32Lys
- gnomAD rs1243073913
- Missense
- Variant Prioritization Score for Impact Estimate 0.65
- REVEL 0.52
- CADD 33.00
- PolyPhen-2 0.56
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available