A2T (p.Ala2Thr) variant of CDK9 (Cyclin-dependent kinase 9)
A2T (p.Ala2Thr) in CDK9 (Cyclin-dependent kinase 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
A2T (p.Ala2Thr) variant details
- p.Ala2Thr
- TOPMed rs1290827114
- gnomAD rs1290827114
- Missense
- Variant Prioritization Score for Impact Estimate 0.318
- REVEL 0.10
- CADD 23.00
- PolyPhen-2 0.03
- SIFT 0.28
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available