Y13D (p.Tyr13Asp) variant of CDK6 (Cyclin-dependent kinase 6)
Y13D (p.Tyr13Asp) in CDK6 (Cyclin-dependent kinase 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
Y13D (p.Tyr13Asp) variant details
- p.Tyr13Asp
- Ensembl rs2116034519
- Missense
- Variant Prioritization Score for Impact Estimate 0.627
- REVEL 0.64
- MetaLR 0.53
- MetaSVM 0.06
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available