R44C (p.Arg44Cys) variant of CDK6 (Cyclin-dependent kinase 6)
R44C (p.Arg44Cys) in CDK6 (Cyclin-dependent kinase 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
R44C (p.Arg44Cys) variant details
- p.Arg44Cys
- cosmic curated COSV10505
- Ensembl rs2116032766
- Missense
- Variant Prioritization Score for Impact Estimate 0.398
- REVEL 0.21
- MetaLR 0.08
- MetaSVM -1.01
- CADD 24.30
- PolyPhen-2 0.07
- SIFT 0.06
- Population evidence available
- Structural context available