R38G (p.Arg38Gly) variant of CDK6 (Cyclin-dependent kinase 6)
R38G (p.Arg38Gly) in CDK6 (Cyclin-dependent kinase 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
R38G (p.Arg38Gly) variant details
- p.Arg38Gly
- ExAC rs759338099
- gnomAD rs759338099
- Missense
- Variant Prioritization Score for Impact Estimate 0.507
- REVEL 0.35
- MetaLR 0.22
- MetaSVM -0.65
- CADD 32.00
- PolyPhen-2 0.79
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available