Q11R (p.Gln11Arg) variant of CDK6 (Cyclin-dependent kinase 6)
Q11R (p.Gln11Arg) in CDK6 (Cyclin-dependent kinase 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
Q11R (p.Gln11Arg) variant details
- p.Gln11Arg
- ExAC rs755309013
- gnomAD rs755309013
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.06
- MetaLR 0.07
- MetaSVM -1.06
- CADD 22.90
- PolyPhen-2 0.02
- SIFT 0.38
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available