L6Q (p.Leu6Gln) variant of CDK6 (Cyclin-dependent kinase 6)
L6Q (p.Leu6Gln) in CDK6 (Cyclin-dependent kinase 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
L6Q (p.Leu6Gln) variant details
- p.Leu6Gln
- Ensembl rs2116034852
- Missense
- Variant Prioritization Score for Impact Estimate 0.369
- REVEL 0.24
- MetaLR 0.20
- MetaSVM -0.94
- CADD 24.50
- PolyPhen-2 0.03
- SIFT 0.11
- Population evidence available
- Structural context available