K26R (p.Lys26Arg) variant of CDK6 (Cyclin-dependent kinase 6)
K26R (p.Lys26Arg) in CDK6 (Cyclin-dependent kinase 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
K26R (p.Lys26Arg) variant details
- p.Lys26Arg
- Ensembl rs2116033701
- Missense
- Variant Prioritization Score for Impact Estimate 0.334
- REVEL 0.16
- MetaLR 0.17
- MetaSVM -0.79
- CADD 25.10
- PolyPhen-2 0.03
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available