G5S (p.Gly5Ser) variant of CDK6 (Cyclin-dependent kinase 6)
G5S (p.Gly5Ser) in CDK6 (Cyclin-dependent kinase 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
G5S (p.Gly5Ser) variant details
- p.Gly5Ser
- cosmic curated COSV56014
- 1000Genomes rs576150359
- ExAC rs576150359
- gnomAD rs576150359
- Missense
- Variant Prioritization Score for Impact Estimate 0.173
- REVEL 0.07
- MetaLR 0.16
- MetaSVM -1.00
- CADD 16.20
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the 1KG:PEL population (allele frequency 0.0059)
- Structural context available