G5R (p.Gly5Arg) variant of CDK6 (Cyclin-dependent kinase 6)
G5R (p.Gly5Arg) in CDK6 (Cyclin-dependent kinase 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
G5R (p.Gly5Arg) variant details
- p.Gly5Arg
- 1000Genomes rs576150359
- ExAC rs576150359
- gnomAD rs576150359
- Missense
- Variant Prioritization Score for Impact Estimate 0.198
- REVEL 0.11
- MetaLR 0.20
- MetaSVM -0.86
- CADD 20.10
- PolyPhen-2 0.00
- SIFT 0.24
- Most common in the South Asian population (allele frequency 2.4e-05)
- Structural context available