G5D (p.Gly5Asp) variant of CDK6 (Cyclin-dependent kinase 6)
G5D (p.Gly5Asp) in CDK6 (Cyclin-dependent kinase 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
G5D (p.Gly5Asp) variant details
- p.Gly5Asp
- Ensembl rs2116034905
- Missense
- Variant Prioritization Score for Impact Estimate 0.373
- REVEL 0.14
- MetaLR 0.26
- MetaSVM -0.51
- CADD 22.80
- PolyPhen-2 0.03
- SIFT 0.51
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.1e-05)
- Structural context available