G36E (p.Gly36Glu) variant of CDK6 (Cyclin-dependent kinase 6)
G36E (p.Gly36Glu) in CDK6 (Cyclin-dependent kinase 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
G36E (p.Gly36Glu) variant details
- p.Gly36Glu
- gnomAD rs1383556587
- Missense
- Variant Prioritization Score for Impact Estimate 0.387
- REVEL 0.18
- MetaLR 0.17
- MetaSVM -0.87
- CADD 22.50
- PolyPhen-2 0.00
- SIFT 0.57
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available