G25V (p.Gly25Val) variant of CDK6 (Cyclin-dependent kinase 6)
G25V (p.Gly25Val) in CDK6 (Cyclin-dependent kinase 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
G25V (p.Gly25Val) variant details
- p.Gly25Val
- cosmic curated COSV56008
- Missense
- Variant Prioritization Score for Impact Estimate 0.742
- REVEL 0.71
- MetaLR 0.66
- MetaSVM 0.60
- CADD 27.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available