F39V (p.Phe39Val) variant of CDK6 (Cyclin-dependent kinase 6)
F39V (p.Phe39Val) in CDK6 (Cyclin-dependent kinase 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
F39V (p.Phe39Val) variant details
- p.Phe39Val
- Ensembl rs2116033035
- Missense
- Variant Prioritization Score for Impact Estimate 0.474
- REVEL 0.41
- MetaLR 0.19
- MetaSVM -0.86
- CADD 27.80
- PolyPhen-2 0.96
- SIFT 0.21
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available